Request a Reliance Agreement

A Reliance Agreement is a written agreement between institutions that identifies which institution will serve as the Reviewing IRB and which will cede IRB review i.e., the Relying Institution. Complete this request form if you are an NIH PI/designee that needs NIH to rely on an external IRB, or you want to request for an external site(s) to rely on the NIH IRB. 

This form can only be used to add up to 10 pSITES.  However, if you have not confirmed that the NIH IRB can review for a study with more than 5 pSITES, contact the Reliance and sIRB team at BEFORE starting on this form. 

Reliance Agreement Request Form

Please contact the NIH Reliance and Single IRB Team with any other questions:

For guidelines submitting a reliance agreement request, please go to:

Guidelines for NIH Study Teams completing the NIH Reliance Agreement Request Form