Office of Human Subjects Research Protections

The Office of Human Subjects Research Protections (OHSRP) carries out the day-to-day operations and regulatory oversight of human research activities within the Human Research Protections Program (HRPP). The OHSRP promotes the protection of rights, safety and welfare of human subjects, and the NIH’s research mandate.


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Office of IRB Operations



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Compliance and Training



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Policy and Accreditation




OHSRP's Vision



We will promote the safe and ethical conduct of human subjects research by

providing timely, consistent and compliant reviews

educating our community

communicating effectively and responsively

collaborating with stakeholders

and thus will be recognized as national leaders in human subjects research protections.




AAHRPP accreditation seal



NIH Federalwide Assurance
FWA #: 00005897
Expires: 07/16/2023
IORG #: 00010