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Ancillary Review

Ancillary reviews are reviews by additional committees or groups that may be required before IRB review and/or approval. The entities that need to provide a review will vary based on the protocol. Some commonly required ancillary reviews are summarized below. As an investigator, you should be aware of the additional ancillary reviews required and ensure these are completed and documented in PROTECT.

Before IRB Review: Additional Requirements

  • Scientific Review

    Clinical protocols in the NIH Intramural Research Program that require IRB approval must undergo scientific review at the Institute/Center (IC) level…

  • NIH Technology Transfer

    NIH technology transfer helps move discoveries and inventions from NIH labs to public and private sectors for commercialization and public benefit.

  • Radiation Safety Committee & Radioactive Drug Research Committee

    Scans, tests, and procedures involving radiation that are specified in the protocol are considered research procedures by the Institutional Review Bo…

  • Conflict of Interest Review

    The Federal Government aims to eliminate or minimize actual or perceived conflicts of interest (COI) in clinical research to promote objectivity and …

  • NIH Institutional Biosafety Committee

    The NIH Institutional Biosafety Committee (IBC) reviews and approves research protocols involving rDNA techniques or potentially infectious/toxic mat…

  • Protocol Resource Impact Assessment (PRIA)

    The PRIA is a prospective review to ensure that the Clinical Center (CC) has the expertise, equipment, and resources needed to successfully conduct c…

  • NIH Human Fetal Tissue Review

    The Human Fetal Tissue (HFT) ancillary review ensures that HFT is used only when scientifically justifiable.

Policies

106 - Policy - Ancillary Reviews

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